1:
Out of all of the Stranger missions, the happiest one has আপনি reunite a zoophile with his পছন্দ horse. Almost all of them are grim and depressing, and when আপনি do the "right" thing, আপনি often end up making people's lives worse. আপনি give Jenny some medicine but she doesn't go with আপনি to town, is left wondering around forever. The guy who আপনি helped make his flying mechine only ends up dying. And Sam slowly loses his mind in his journey to California.


#2:
Birth of the Conservation Movement. You've just killed all but one of the peaceful Sasquatch, and the last one is distraught and begging আপনি to kill him. It's up to আপনি to decide whether অথবা not to oblige him. All because some যেভাবে খুশী crazy guy told আপনি they ate babies. Nice one, Marston.
Least there's a easteregg in GTA 5, where the parody this scene, where it was a guy dressed up as one, and even barks for some reason.


#3:
Seth হারিয়ে গেছে his family, business, and his sanity in a খুঁজুন for treasure.. And in the end all he got was a glass eye.


#4:
Almost everything about UNDEAD NIGHTMARE:
আপনি were forced to kill your family friend. Your own wife and child have become ravenous, flesh-eating ghouls, as have thousands of people across the West. Once serene (well, for the most part) settlements have become fortresses against the shambling hordes, their residents dwindling in numbers. Ammo, as well as allies, are scarce. And you've got to set out into the deadly, zombie-filled land to find a cure. And along the way beloved characters are dying at every corner,


#5:
when John confronts Dutch, he tries to convince Dutch to stop fighting and just give up, but Dutch says it's not possible. When John says that mean he has to kill Dutch, Dutch tells him "when I'm gone, they'll just find another monster". And just before throwing himself to his death, in a weak and defeated voice, he says "Our time has passed, John". When আপনি finally return প্রথমপাতা it doesn't take long for the army to betray John, just as Dutch ব্যক্ত they would.


#6:
Nastas' abrupt, pointless death. It doesn't help he's one of the few decent characters in the game.


#7:
osing one of your horses, if you've gotten used to it. Even moreso if it's the golden horse আপনি get specially during one of the missions. Good news is আপনি can quickly quit the game, অথবা আরো easily, just have Marston get killed, and when he respawns the horse আপনি got attached to will be back as well.


#8:
Drew McFarlene saying "I buried আরো of my childrun than I raised.


#9:
Killing that corrupt asshole Edgar Ross was quite awesome wasn't it? Well it is until আপনি realize John died in vein. Jack has become what John was. A gunslinger. However. The mission is entirely optional. The player, not Jack, ultimately chooses whether অথবা not John's sacrifice was in vain. And considering when Jack বন্দুক down Ross, he is only left feeling empty. Realizing he was no better than Ross.


#10:
The fact John nievely thinks that he can live a peaceful life, despite his criminal history.